Coronavirus: Adults and many children were found with antibodies without being ill

Scientists in Britain, led by two Greeks in the diaspora, have found that a percentage of people – especially young people – who have never been infected with the SARS-CoV-2 coronavirus and therefore have not contracted Covid-19 disease have a relative natural immunity thanks to Researchers, led by George Cassiotis of the Francis Creek Institute in London and Eleni Nastouli of University College London, USA, led by published in the journal Science, found that among 302 adults examined, 16 (5.3%) had IgG antibodies to SARS-CoV-2, possibly developed during infections in the past by the much more malignant seasonal coronaviruses of the common cold. Also, among 48 children and adolescents aged one to 16 years studied, similar antibodies were detected in 21 (44%). These pre-existing antibodies react to a specific region (the so-called S2 subunit) of the protruding spike protein of the new coronavirus, which it uses to penetrate and infect human cells. The S2 subunit shows greater structural similarities in all coronaviruses than the S1 subunit of the same viral protein. The presence of pre-existing antibodies can reduce the transmission of the virus and alleviate the symptoms in case of infection. Experiments with cell cultures in the laboratory showed that the blood plasma of both adults and children with antibodies without being infected with Covid-19, could fight the new coronavirus. This was not the case with plasma from individuals without such pre-existing antibodies. “Works” against many coronaviruses rapidly. By comparison, those infected with SARS-CoV-2 develop higher numbers of all antibody types (IgA, IgG and IgM), targeting both the S1 and S2 subunits. Source: ΑΠΕ-ΜΠΕ Follow it on Google News and be the first to know all the news See all the latest News from Greece and the World, at

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